Research overview

There are several research efforts in the laboratory which are all directed at understanding – at the molecular level - the various mechanisms and principles that allow populations of bacteria to adapt to and survive in dynamic environments in general and in the context of host-pathogen interactions in particular. Such adaptive principles may include both genetically ‘programmed’ responses such as cell differentiation and gene expression as well as adaptive evolutionary changes where the genetic composition of a bacterial population changes as a result of mutation and natural selection.

Keywords:

Bacterial genomics, Microbial interactions, Evolution, Physiological and genetic variations in bacterial populations.

Student projects

Please contact me () if you would like to do a project in the lab.

Most recent completed projects:
“Genome scale mutation discovery” (Master project – August 09)
“Genome sequencing and analysis of a Roseobacter genome (Special project in collaboration with Lone Gram – December 09)

Current research topics

Persistent P. aeruginosa infections in animals and humans

Detailed description

System-independent properties of persistent bacterial-host interactions

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In situ evolution of successful persistent colonizer of CF airways

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Genome scale mutation discovery

Detailed description